Plagl1 and Lrrc58 control mammalian body size by triggering target-directed microRNA degradation of miR-322 and miR-503 [Research Papers]
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Read Full ArticleIn this study, LaVigne et al. identify Plagl1, Lrrc58, and Malat1 as trigger RNAs for the ZSWIM8-mediated, target-directed microRNA degradation (TDMD) of miR-322-5p and miR-503-p, respectively. The work highlights how such noncoding functions of these mRNAs, …
Written by: LaVigne, C. A., Han, J., Zhang, H., Cho, S., Kim, M., Sethia, K., Evers, B. M., Acharya, A., Chang, T.-C., Mendell, J. T.
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