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Mechanistic insights and in vivo HIV suppression by the BRD4-targeting small molecule ZL0580

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Mechanistic insights and in vivo HIV suppression by the BRD4-targeting small molecule ZL0580
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Author summary Current HIV therapies effectively suppress viral replication but do not eradicate the virus, necessitating lifelong treatment. A promising strategy for achieving durable remission is the “block and lock” approach, which aims to silence HIV thro…

Written by: Naveen Kumar, Zonghui Ma, Fuquan Long, Srinivasa Reddy Bonam, Hsien-Tsung Lai, Shwu-Yuan Wu, Haiying Chen, Nicholas C. Hazell, Jiani Bei, Xuefeng Liu, Yeqing Chen, Zhi Wei, Cheng-Ming Chiang, Jia Zhou, Haitao Hu

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